What Is CJC-1295 (No DAC) + Ipamorelin Blend?
A research guide to CJC-1295 (No DAC) + Ipamorelin Blend: what it is at a laboratory level, the preclinical receptor pathways it is studied for, and how to verify batch quality. Supplied for laboratory and research use only, Australia.
What is CJC-1295 (No DAC) + Ipamorelin Blend?
CJC-1295 (No DAC) + Ipamorelin Blend is supplied strictly for laboratory and research use only. It is not intended for use in humans or animals, and nothing on this page describes any form of consumption, administration or applied use. The information below characterises what the material is at a laboratory level and why it draws interest as a research reagent.
This product is a co-formulated blend of two distinct synthetic peptides that are frequently studied together in laboratory settings. The first, CJC-1295 without DAC (sometimes written as modified GRF 1-29 or Mod-GRF 1-29), is a truncated analogue of growth hormone releasing hormone. The No DAC designation indicates the absence of the Drug Affinity Complex modification, so the molecule lacks the maleimido group that, in the DAC variant, is described in the literature as promoting binding to albumin and a longer in-solution stability window in laboratory conditions.
The second component, Ipamorelin, is a synthetic pentapeptide belonging to the growth hormone secretagogue class. It is structurally described as a short peptide often summarised by the sequence Aib-His-D-2-Nal-D-Phe-Lys. As a class, both molecules are studied for how they interact with receptor pathways associated with the somatotropic axis. Because the two are characterised as acting on complementary receptor targets in preclinical models, the growth hormone releasing hormone receptor and the growth hormone secretagogue receptor, they are commonly investigated as a paired blend within the same research workflow.
You can review the listing and specifications for this material here: View CJC-1295 (No DAC) + Ipamorelin Blend.
Why researchers study this blend
Interest in this combination is entirely preclinical and mechanistic. Laboratories characterise these peptides to understand how synthetic secretagogues and releasing hormone analogues interact with their respective receptors in cell based assays and other preclinical models. The appeal of pairing them lies in studying two separate signalling routes into the same axis within a single experimental design.
Researchers typically frame their questions around the following areas of investigation:
- Receptor binding and selectivity of growth hormone secretagogues in laboratory receptor assays.
- How growth hormone releasing hormone analogues behave once the DAC albumin-binding modification is removed.
- Comparative pharmacology of paired versus single-agent exposure in preclinical models.
- Structure and stability characterisation of synthetic peptide reagents under controlled conditions.
CJC-1295 (No DAC): the releasing hormone analogue
CJC-1295 (No DAC) is studied as a short analogue of the first 29 amino acids of growth hormone releasing hormone, with substitutions intended to improve resistance to enzymatic breakdown under laboratory conditions. These substitutions are what distinguish it from the unmodified native fragment, and they are a common focus of stability and identity studies.
Because the No DAC form omits the albumin-binding complex, it is often selected in research where a shorter acting releasing hormone analogue is preferable for a given experimental window. Investigators studying the growth hormone releasing hormone receptor pathway use it to probe receptor engagement within the somatotropic axis research category, always within preclinical and in vitro frameworks rather than any applied setting.
Ipamorelin: the selective secretagogue
Ipamorelin is investigated as a growth hormone secretagogue receptor ligand. In the research literature it is frequently described as a comparatively selective agonist within its class, which is one reason it is a popular reference reagent for studying secretagogue signalling in isolation.
When co-formulated with CJC-1295 (No DAC), the blend allows researchers to examine two mechanistically distinct inputs, a releasing hormone analogue and a secretagogue, side by side. This complementary design is the primary scientific rationale behind studying the two as a single blended reagent rather than sourcing and reconstituting them separately.
How to verify quality
Quality verification is central to responsible research sourcing. A reputable research peptide should arrive with documentation that lets you confirm identity and analytical purity before it enters any workflow. Rather than trusting a claim, you should be able to trace the specific vial back to its own analytical record.
Every Pepology batch is third-party lab tested by Novagen Laboratories, with a certificate of analysis that customers can verify. Analytical work of this kind generally covers identity confirmation, for example by mass spectrometry, alongside purity assessment by high performance liquid chromatography (HPLC). We do not publish invented figures here. The certificate for your specific batch is the authoritative record.
Use this checklist when assessing any research peptide:
- Confirm a certificate of analysis is available for the exact batch you received.
- Check that the lot number printed on the vial matches the lot number on the certificate.
- Look for identity confirmation and an HPLC purity assessment on the document.
- Confirm the testing was carried out by an independent third-party laboratory.
- Independently verify the certificate rather than relying on a screenshot or claim.
Sourcing in Australia and buying with confidence
Pepology is an Australian, Gold Coast owned and operated retailer of research peptides. Sourcing domestically means shorter transit, local accountability and direct access to the certificate of analysis for the batch you receive, which matters when you need traceable, verifiable reagents for laboratory work.
All materials, including CJC-1295 (No DAC) + Ipamorelin Blend, are supplied strictly for laboratory and research use only. They are not for human or animal use and are not offered for any diagnostic, therapeutic or applied purpose. Purchasing from a transparent Australian supplier with independent third-party testing is the most reliable way to know exactly what a vial contains.
To review this reagent or explore the wider catalogue, you can View CJC-1295 (No DAC) + Ipamorelin Blend or Browse all research peptides.
View CJC-1295 (No DAC) + Ipamorelin Blend Browse all research peptides
Frequently asked questions
What is CJC-1295 (No DAC) + Ipamorelin Blend?
It is a co-formulated research reagent combining two synthetic peptides: CJC-1295 without DAC, a truncated growth hormone releasing hormone analogue, and Ipamorelin, a growth hormone secretagogue. It is characterised and studied at a laboratory level only. It is supplied strictly for laboratory and research use.
Is CJC-1295 (No DAC) + Ipamorelin Blend safe to use in humans or animals?
This material is supplied strictly for laboratory and research use only. It is not intended for use in humans or animals and is not offered for any diagnostic, therapeutic or applied purpose. We do not provide dosing, protocols or usage guidance of any kind.
Why do researchers study these two peptides together?
They are characterised as acting on complementary receptor targets in preclinical models, the growth hormone releasing hormone receptor and the growth hormone secretagogue receptor. Studying them as a single blend lets laboratories examine two mechanistically distinct inputs into the same axis within one experimental design, entirely within in vitro and preclinical frameworks.
What does the No DAC designation mean?
No DAC means the molecule lacks the Drug Affinity Complex modification. In the DAC variant this group is described as promoting binding to albumin and a longer in-solution stability window in laboratory conditions. The No DAC form omits it, so it is often selected in research needing a shorter acting releasing hormone analogue.
How do I verify the quality of this research peptide?
Every Pepology batch is third-party lab tested by Novagen Laboratories with a certificate of analysis you can verify. Confirm the lot number on the vial matches the certificate, check it shows identity confirmation and an HPLC purity assessment, and verify it independently rather than trusting a claim or screenshot.
Where can I source CJC-1295 (No DAC) + Ipamorelin Blend in Australia?
Pepology is an Australian, Gold Coast owned and operated retailer of research peptides and supplies this reagent for laboratory and research use only. Buying from a transparent domestic supplier with independent third-party testing gives you a traceable certificate of analysis for the exact batch you receive.
This article is general information for research buyers. All Pepology products are supplied strictly for laboratory research use only and are not for human or animal use. Every batch is independently tested by Novagen Laboratories and verifiable on a public register.